Myasthenia gravis requiring pyridostigmine treatment in a national population cohort
نویسندگان
چکیده
منابع مشابه
Total drug treatment and comorbidity in myasthenia gravis: a population-based cohort study
BACKGROUND AND PURPOSE Comorbidity in myasthenia gravis (MG) is important for diagnosis, treatment and prognosis. Disease complexity was assessed by examining total drug treatment, immune therapy and comorbidity in a complete national MG cohort. METHODS All recipients of the MG-specific drug pyridostigmine 2004-2010 registered in the compulsory Norwegian Prescription Database who met the incl...
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In 18 patients with generalised myasthenia treated with oral pyridostigmine, muscular strength, decrement of neuromuscular transmission in the trapezius muscle on repetitive accessory nerve stimulation, and pyridostigmine plasma level were measured repeatedly during 1-3 dosing intervals. Significant correlations between pyridostigmine concentrations and functional parameters were present in thr...
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A case of myasthenia gravis in a 15 years old girl is pre·sented. The disease was present for 5 years before thymectomy was performed. Indications for thymectomy, preoperative preparation, anesthetic and surgical management is -discussed.
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Myasthenia gravis is a prototypic antibody-mediated neurological autoimmune disorder. Its pathogenesis is much better understood than that of multiple sclerosis or immune neuropathies. Currently two targets in the endplate membrane are considered as autoantigens, the acetylcholine receptor (in up to 90%) and the muscle-specific kinase (MuSK, in about 5%). Fortunately, substantial therapeutic pr...
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A retrospective comparative study was performed on 54 patients treated medically or surgically (thymectomy) for myasthenia gravis (MG) from 1979- 1989 in three Shiraz University Hospitals. Each surgical patient was compared with a medical patient on the basis of age, sex, severity and duration of disease. Complete remission was noted in 3 out of 27 thymectomized patients but in none of the...
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ژورنال
عنوان ژورنال: European Journal of Neurology
سال: 2010
ISSN: 1351-5101
DOI: 10.1111/j.1468-1331.2010.03089.x